Item Type | Name |
Concept
|
Adenoviridae
|
Concept
|
Antigen-Antibody Complex
|
Concept
|
Antigens, Neoplasm
|
Concept
|
Antibiotics, Antineoplastic
|
Concept
|
Antibody-Dependent Cell Cytotoxicity
|
Concept
|
Arthritis, Experimental
|
Concept
|
Anemia, Pernicious
|
Concept
|
Calcimycin
|
Concept
|
Abscess
|
Concept
|
Agammaglobulinemia
|
Concept
|
alpha-Macroglobulins
|
Concept
|
Binding Sites, Antibody
|
Concept
|
Breast Neoplasms
|
Concept
|
Amino Acid Sequence
|
Concept
|
Adenosine Triphosphate
|
Concept
|
Antigens, Differentiation
|
Concept
|
Antineoplastic Agents
|
Concept
|
Antithrombin III
|
Concept
|
Carboxypeptidases
|
Concept
|
Cell Fractionation
|
Concept
|
Animals
|
Concept
|
Quaternary Ammonium Compounds
|
Concept
|
Chondrosarcoma
|
Concept
|
Epitopes
|
Concept
|
Antibodies, Anti-Idiotypic
|
Concept
|
Antibodies, Monoclonal
|
Concept
|
Antigens, Differentiation, T-Lymphocyte
|
Concept
|
Arthritis, Rheumatoid
|
Concept
|
Cytoplasmic Granules
|
Concept
|
Antigens, Differentiation, B-Lymphocyte
|
Concept
|
Antilymphocyte Serum
|
Concept
|
B-Lymphocytes
|
Concept
|
Base Sequence
|
Concept
|
Cell Nucleus
|
Concept
|
Aspirin
|
Concept
|
Autoantigens
|
Concept
|
DNA Damage
|
Concept
|
Chondroitin Sulfates
|
Concept
|
Carcinoma, Renal Cell
|
Concept
|
Autoantibodies
|
Concept
|
Binding Sites
|
Concept
|
beta-Endorphin
|
Concept
|
Bicarbonates
|
Concept
|
Brucella
|
Concept
|
Cattle
|
Concept
|
Cell Membrane
|
Concept
|
Cell Separation
|
Concept
|
Chromatography, Gel
|
Concept
|
Chromium Radioisotopes
|
Concept
|
Clone Cells
|
Concept
|
Cell Transformation, Viral
|
Concept
|
Cell-Free System
|
Concept
|
Cholic Acids
|
Concept
|
Cardiolipins
|
Concept
|
Cartilage, Articular
|
Concept
|
Cell Adhesion
|
Concept
|
Colonic Neoplasms
|
Concept
|
Chromium
|
Concept
|
Colicins
|
Concept
|
Cholesterol
|
Concept
|
Clathrin
|
Concept
|
Collagen
|
Concept
|
Cytosol
|
Concept
|
Culture Media
|
Concept
|
Immunoglobulin M
|
Concept
|
Cysteine Endopeptidases
|
Concept
|
Cytochrome c Group
|
Concept
|
Cytoplasm
|
Concept
|
Detergents
|
Concept
|
Injections, Intraperitoneal
|
Concept
|
Interleukin-2
|
Concept
|
Cytomegalovirus Infections
|
Concept
|
Cytoskeleton
|
Concept
|
Cytotoxicity, Immunologic
|
Concept
|
DNA Repair
|
Concept
|
Cathepsins
|
Concept
|
Cytotoxicity Tests, Immunologic
|
Concept
|
Cytotoxins
|
Concept
|
Endorphins
|
Concept
|
Immunoglobulin A
|
Concept
|
Immunoglobulin Fc Fragments
|
Concept
|
Etoposide
|
Concept
|
Extracellular Space
|
Concept
|
Cobalt
|
Concept
|
Cocaine
|
Concept
|
Dextrans
|
Concept
|
Cytomegalovirus
|
Concept
|
Melitten
|
Concept
|
Infant, Newborn
|
Concept
|
Egtazic Acid
|
Concept
|
Mice, Inbred C3H
|
Concept
|
Models, Chemical
|
Concept
|
Fluorescence
|
Concept
|
Myasthenia Gravis
|
Concept
|
Nasal Septum
|
Concept
|
Fibronectins
|
Concept
|
Ions
|
Concept
|
Killer Cells, Natural
|
Concept
|
Graft Rejection
|
Concept
|
Hemolysis
|
Concept
|
DNA Replication
|
Concept
|
Dose-Response Relationship, Drug
|
Concept
|
Immune Sera
|
Concept
|
Leukemia, Experimental
|
Concept
|
Liposomes
|
Concept
|
Immune Tolerance
|
Concept
|
Infectious Mononucleosis
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
Concept
|
Epithelium
|
Concept
|
Herpesvirus 4, Human
|
Concept
|
Flow Cytometry
|
Concept
|
Fluorescent Antibody Technique
|
Concept
|
Immunity, Cellular
|
Concept
|
Inflammation
|
Concept
|
Immunodiffusion
|
Concept
|
Genes, MHC Class I
|
Concept
|
Leukocytes, Mononuclear
|
Concept
|
Light
|
Concept
|
Macrophages
|
Concept
|
Lymphocytic Choriomeningitis
|
Concept
|
Intracellular Fluid
|
Concept
|
Membrane Glycoproteins
|
Concept
|
Lymphocyte Culture Test, Mixed
|
Concept
|
Mice, Inbred Strains
|
Concept
|
Models, Molecular
|
Concept
|
Phospholipids
|
Concept
|
Lymphocytic choriomeningitis virus
|
Concept
|
Naphthoquinones
|
Concept
|
Mice, Transgenic
|
Concept
|
Extracellular Matrix
|
Concept
|
Immunohistochemistry
|
Concept
|
Molecular Sequence Data
|
Concept
|
Mycobacterium tuberculosis
|
Concept
|
Necrosis
|
Concept
|
Mice, Inbred BALB C
|
Concept
|
Mice, Inbred C57BL
|
Concept
|
Mitogens
|
Concept
|
Mycobacterium
|
Concept
|
Cricetinae
|
Concept
|
Heat-Shock Proteins
|
Concept
|
HeLa Cells
|
Concept
|
Hemolysin Proteins
|
Concept
|
Hepatitis
|
Concept
|
Penicillamine
|
Concept
|
Neutrophils
|
Concept
|
Laminin
|
Concept
|
Phagocytosis
|
Concept
|
Lipid Bilayers
|
Concept
|
Lymphokines
|
Concept
|
Peptide Hydrolases
|
Concept
|
Membrane Lipids
|
Concept
|
Endopeptidases
|
Concept
|
Phytohemagglutinins
|
Concept
|
Mouth
|
Concept
|
Myeloma Proteins
|
Concept
|
Naloxone
|
Concept
|
Osteogenesis
|
Concept
|
Parenteral Nutrition
|
Concept
|
Tetracycline
|
Concept
|
Prednisone
|
Concept
|
Prostatic Neoplasms
|
Concept
|
Poloxalene
|
Concept
|
Protein Conformation
|
Concept
|
Protease Inhibitors
|
Concept
|
Gamma Rays
|
Concept
|
Idoxuridine
|
Concept
|
Immunoglobulin G
|
Concept
|
Rats, Inbred F344
|
Concept
|
Receptors, Fc
|
Concept
|
Recurrence
|
Concept
|
Regression Analysis
|
Concept
|
Rabbits
|
Concept
|
Rosette Formation
|
Concept
|
Rubidium
|
Concept
|
Trypsin Inhibitors
|
Concept
|
Pyruvates
|
Concept
|
Receptors, Immunologic
|
Concept
|
Virion
|
Concept
|
Vitamin B 12
|
Concept
|
Interferon-gamma
|
Concept
|
Receptors, Transferrin
|
Concept
|
Ribonucleoproteins
|
Concept
|
Serpins
|
Concept
|
Interleukin-6
|
Concept
|
Salmonella typhimurium
|
Concept
|
Sensitivity and Specificity
|
Concept
|
Thrombin
|
Concept
|
Thymidine
|
Concept
|
Sheep
|
Concept
|
Sulfates
|
Concept
|
Humans
|
Concept
|
Hypercholesterolemia
|
Concept
|
Hypoprothrombinemias
|
Concept
|
Transcription, Genetic
|
Concept
|
Protein Biosynthesis
|
Concept
|
Software
|
Concept
|
Streptolysins
|
Concept
|
Interferon Type I
|
Concept
|
Intracellular Membranes
|
Concept
|
CHO Cells
|
Concept
|
Sudden Infant Death
|
Concept
|
Synovial Membrane
|
Concept
|
Tumor Necrosis Factor-alpha
|
Concept
|
Sequence Homology, Amino Acid
|
Concept
|
Receptors, IgG
|
Concept
|
Dinoprostone
|
Concept
|
Iodine Radioisotopes
|
Concept
|
Kidney Glomerulus
|
Concept
|
Liver Neoplasms, Experimental
|
Concept
|
Lysosomes
|
Concept
|
Herpesvirus 1, Human
|
Concept
|
Complement Membrane Attack Complex
|
Concept
|
Cell Culture Techniques
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
Concept
|
Caspases
|
Concept
|
Cryoelectron Microscopy
|
Concept
|
rab5 GTP-Binding Proteins
|
Concept
|
Tumor Cells, Cultured
|
Concept
|
Virus Cultivation
|
Concept
|
NF-kappa B
|
Concept
|
Receptors, Interleukin-2
|
Concept
|
Antigens, CD
|
Concept
|
Receptors, Antigen, T-Cell, gamma-delta
|
Concept
|
Lymphoma
|
Concept
|
Microinjections
|
Concept
|
Mitochondria
|
Concept
|
Multiple Myeloma
|
Concept
|
CD4-Positive T-Lymphocytes
|
Concept
|
Interleukin-8
|
Concept
|
Culture Media, Conditioned
|
Concept
|
Gene Expression
|
Concept
|
Rats, Wistar
|
Concept
|
Mutagenesis, Site-Directed
|
Concept
|
T-Lymphocyte Subsets
|
Concept
|
Protein Structure, Tertiary
|
Concept
|
Melanoma
|
Concept
|
Metacarpophalangeal Joint
|
Concept
|
Microscopy, Electron, Scanning
|
Concept
|
Microtubules
|
Concept
|
Lupus Coagulation Inhibitor
|
Concept
|
Treatment Outcome
|
Concept
|
Neoplasms, Experimental
|
Concept
|
Neutralization Tests
|
Concept
|
Fluorescein-5-isothiocyanate
|
Concept
|
Annexin A5
|
Concept
|
Gene Deletion
|
Concept
|
Mice, Knockout
|
Concept
|
CD8-Positive T-Lymphocytes
|
Concept
|
DNA, Complementary
|
Concept
|
Receptors, Thrombin
|
Concept
|
Models, Immunological
|
Concept
|
Caspase 3
|
Concept
|
Caspase 7
|
Concept
|
Fas Ligand Protein
|
Concept
|
Heparan Sulfate Proteoglycans
|
Concept
|
Mutation, Missense
|
Concept
|
Unilamellar Liposomes
|
Concept
|
Lymphocyte Count
|
Concept
|
Epitopes, T-Lymphocyte
|
Concept
|
Jurkat Cells
|
Concept
|
Protein Structure, Secondary
|
Concept
|
Octoxynol
|
Concept
|
Receptors, Purinergic P2X7
|
Concept
|
COS Cells
|
Concept
|
Microscopy, Confocal
|
Concept
|
Amino Acid Substitution
|
Concept
|
Caspase 1
|
Concept
|
Pyruvic Acid
|
Concept
|
Interleukin-1beta
|
Concept
|
Interleukin 1 Receptor Antagonist Protein
|
Concept
|
RNA, Small Cytoplasmic
|
Concept
|
Cyclophilins
|
Concept
|
Plasma
|
Concept
|
Prostaglandins E
|
Concept
|
Polyradiculoneuropathy
|
Concept
|
Precipitin Tests
|
Concept
|
Chondroitin Sulfate Proteoglycans
|
Concept
|
Mice
|
Concept
|
Caspase 8
|
Concept
|
Fas-Associated Death Domain Protein
|
Concept
|
Endosomes
|
Concept
|
Rheumatoid Factor
|
Concept
|
Saliva
|
Concept
|
Chymases
|
Concept
|
DNA Fragmentation
|
Concept
|
Research Design
|
Concept
|
Retinal Artery
|
Concept
|
RNA, Messenger
|
Concept
|
Lamin Type A
|
Concept
|
Sodium Chloride
|
Concept
|
Specimen Handling
|
Concept
|
Host-Pathogen Interactions
|
Concept
|
Multiprotein Complexes
|
Concept
|
Rats
|
Concept
|
Static Electricity
|
Concept
|
Trypsin
|
Concept
|
Spleen
|
Concept
|
Subcellular Fractions
|
Concept
|
Vero Cells
|
Concept
|
Adaptor Proteins, Signal Transducing
|
Concept
|
T-Lymphocytes, Cytotoxic
|
Concept
|
Immunoblotting
|
Concept
|
Blotting, Western
|
Concept
|
Serine Proteinase Inhibitors
|
Concept
|
Tubulin
|
Concept
|
Receptors, Interleukin-1
|
Concept
|
Receptor, IGF Type 2
|
Concept
|
Killer Cells, Lymphokine-Activated
|
Concept
|
Simplexvirus
|
Concept
|
Herpesvirus 2, Human
|
Concept
|
Lymphocyte Subsets
|
Concept
|
HL-60 Cells
|
Concept
|
GTP-Binding Proteins
|
Concept
|
Secretory Vesicles
|
Concept
|
snRNP Core Proteins
|
Concept
|
Gene Knockdown Techniques
|
Concept
|
Phosphatidylinositol 3-Kinases
|
Concept
|
K562 Cells
|
Concept
|
Inhibitory Concentration 50
|
Concept
|
Caenorhabditis elegans Proteins
|
Concept
|
MAP Kinase Signaling System
|
Concept
|
Isocoumarins
|
Concept
|
T-Lymphocytes, Regulatory
|
Concept
|
CASP8 and FADD-Like Apoptosis Regulating Protein
|
Concept
|
Tryptases
|
Concept
|
Granzymes
|
Concept
|
Dynamins
|
Concept
|
RNA, Small Interfering
|
Concept
|
Lectins, C-Type
|
Concept
|
Cytochromes c
|
Concept
|
Cell Line, Tumor
|
Concept
|
Pore Forming Cytotoxic Proteins
|
Concept
|
Caspase 6
|
Concept
|
Caspase 10
|
Concept
|
Aggrecans
|
Concept
|
Perforin
|
Concept
|
Antibodies, Neutralizing
|
Concept
|
Antibodies
|
Concept
|
Antineoplastic Agents, Phytogenic
|
Concept
|
Antibodies, Antinuclear
|
Concept
|
Arthritis, Juvenile
|
Concept
|
Aurintricarboxylic Acid
|
Concept
|
Binding, Competitive
|
Concept
|
Calcium
|
Concept
|
Cell Line
|
Concept
|
Cell Nucleolus
|
Concept
|
Cells, Cultured
|
Concept
|
Chlamydia Infections
|
Concept
|
Chymotrypsin
|
Concept
|
Coumarins
|
Concept
|
Delayed-Action Preparations
|
Concept
|
Disease Models, Animal
|
Concept
|
DNA, Single-Stranded
|
Concept
|
Doxorubicin
|
Concept
|
Drug Screening Assays, Antitumor
|
Concept
|
Enkephalin, Methionine
|
Concept
|
Erythrocytes
|
Concept
|
Esterases
|
Concept
|
Fluorescent Dyes
|
Concept
|
Immunologic Memory
|
Concept
|
Injections, Subcutaneous
|
Concept
|
Longitudinal Studies
|
Concept
|
Lymphocyte Activation
|
Concept
|
Lymphocytes
|
Concept
|
Membrane Potentials
|
Concept
|
Microscopy, Fluorescence
|
Concept
|
Models, Biological
|
Concept
|
Monocytes
|
Concept
|
Nuclear Envelope
|
Concept
|
Phosphatidylserines
|
Concept
|
Receptors, Antigen, T-Cell
|
Concept
|
Receptors, Opioid
|
Concept
|
Retrospective Studies
|
Concept
|
Sclerosis
|
Concept
|
Serine Endopeptidases
|
Concept
|
Staining and Labeling
|
Concept
|
Synovial Fluid
|
Concept
|
T-Lymphocytes
|
Concept
|
Uveal Neoplasms
|
Concept
|
Leukemia, T-Cell
|
Concept
|
HIV-1
|
Concept
|
Immunophenotyping
|
Concept
|
Cytokines
|
Concept
|
Bacteremia
|
Concept
|
Ribonucleoproteins, Small Nuclear
|
Concept
|
DNA Primers
|
Concept
|
Deltaretrovirus
|
Concept
|
Gelsolin
|
Concept
|
Macrolides
|
Concept
|
fas Receptor
|
Concept
|
U937 Cells
|
Concept
|
Membrane Microdomains
|
Concept
|
Fluorescence Resonance Energy Transfer
|
Concept
|
Vesicular Transport Proteins
|
Concept
|
Cathepsin A
|
Concept
|
Proto-Oncogene Proteins c-akt
|
Concept
|
Membrane Potential, Mitochondrial
|
Concept
|
Caspase 9
|
Academic Article
|
ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B.
|
Academic Article
|
The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A.
|
Academic Article
|
Routine measurement of IgM, IgG, and IgA rheumatoid factors: high sensitivity, specificity, and predictive value for rheumatoid arthritis.
|
Academic Article
|
New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis.
|
Academic Article
|
Synthesis and evaluation of diphenyl phosphonate esters as inhibitors of the trypsin-like granzymes A and K and mast cell tryptase.
|
Academic Article
|
An antimicrobial activity of cytolytic T cells mediated by granulysin.
|
Academic Article
|
Granzyme B independently of perforin mediates noncytolytic intracellular inactivation of vesicular stomatitis virus.
|
Academic Article
|
Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7.
|
Academic Article
|
Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly(ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment.
|
Academic Article
|
Human perforin: rapid enrichment by immobilized metal affinity chromatography (IMAC) for whole cell cytotoxicity assays.
|
Academic Article
|
Nuclear targeting of the serine protease granzyme A (fragmentin-1).
|
Academic Article
|
BCL-2 blocks perforin-induced nuclear translocation of granzymes concomitant with protection against the nuclear events of apoptosis.
|
Academic Article
|
P-glycoprotein does not protect cells against cytolysis induced by pore-forming proteins.
|
Academic Article
|
Extracellular granzyme A, complexed to proteoglycans, is protected against inactivation by protease inhibitors.
|
Academic Article
|
Purification and use of granzyme B.
|
Academic Article
|
Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis.
|
Academic Article
|
Pro-caspase-3 is a major physiologic target of caspase-8.
|
Academic Article
|
HSV and glycoprotein J inhibit caspase activation and apoptosis induced by granzyme B or Fas.
|
Academic Article
|
Activation of a cysteine protease in MCF-7 and T47D breast cancer cells during beta-lapachone-mediated apoptosis.
|
Academic Article
|
Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation.
|
Academic Article
|
Cell death-associated translocation of plasma membrane components induced by CTL.
|
Academic Article
|
HIV virions and HIV infection in vitro are unaffected by human granzymes A and B.
|
Academic Article
|
Flow cytometry cannot assess surface binding of perforin to target cells.
|
Academic Article
|
A distinct pathway of cell-mediated apoptosis initiated by granulysin.
|
Academic Article
|
Reconstitution of caspase 3 sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis.
|
Academic Article
|
NF-kappaB protects from the lysosomal pathway of cell death.
|
Academic Article
|
Cytotoxic cell granule-mediated apoptosis. Characterization of the macromolecular complex of granzyme B with serglycin.
|
Academic Article
|
Lack of the CD8+ cell anti-HIV factor in CD8+ cell granules.
|
Academic Article
|
The human cytomegalovirus protein UL16 mediates increased resistance to natural killer cell cytotoxicity through resistance to cytolytic proteins.
|
Academic Article
|
Granzyme B-mediated apoptosis--the elephant and the blind men?
|
Academic Article
|
Reconstitution of caspase-3 confers low glucose-enhanced tumor necrosis factor-related apoptosis-inducing ligand cytotoxicity and Akt cleavage.
|
Academic Article
|
Perforin and granzyme B induce apoptosis in FasL-resistant colon carcinoma cells.
|
Academic Article
|
SPI-CI and SPI-6 cooperate in the protection from effector cell-mediated cytotoxicity.
|
Academic Article
|
The T cell death knell: immune-mediated tumor death in renal cell carcinoma.
|
Academic Article
|
A role for the granzyme B inhibitor serine protease inhibitor 6 in CD8+ memory cell homeostasis.
|
Academic Article
|
Myeloma cells are highly sensitive to the granule exocytosis pathway mediated by WT1-specific cytotoxic T lymphocytes.
|
Academic Article
|
Human neutrophils lack granzyme A, granzyme B, and perforin.
|
Academic Article
|
A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death.
|
Academic Article
|
Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis.
|
Academic Article
|
Detection of functional cell surface perforin by flow cytometry.
|
Academic Article
|
Granzyme B translocates across the lipid membrane only in the presence of lytic agents.
|
Academic Article
|
Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells.
|
Academic Article
|
Granule-associated serine proteases: granzymes might not just be killer proteases.
|
Academic Article
|
Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin.
|
Academic Article
|
Clinical value of an integrated ELISA system for the detection of 6 autoantibodies (ssDNA, dsDNA, Sm, RNP/Sm, SSA, and SSB).
|
Academic Article
|
Retinal vein thrombosis in a patient with pernicious anemia and anticardiolipin antibodies.
|
Academic Article
|
Granzyme A is a proinflammatory protease.
|
Academic Article
|
Mouse granzyme K has pro-inflammatory potential.
|
Academic Article
|
Intracellular trafficking of perforin: to thwart a killer.
|
Academic Article
|
NK cell protease granzyme M targets alpha-tubulin and disorganizes the microtubule network.
|
Academic Article
|
Lysis of human T cell leukemia virus infected T and B lymphoid cells by interleukin 2-activated killer cells.
|
Academic Article
|
Interleukin-1R signaling is essential for induction of proapoptotic CD8 T cells, viral clearance, and pathology during lymphocytic choriomeningitis virus infection in mice.
|
Academic Article
|
Perforin activity at membranes leads to invaginations and vesicle formation.
|
Academic Article
|
Modulation of the autologous mixed lymphocyte reaction by beta-endorphin.
|
Academic Article
|
Modulation of the tumor cell phenotype by IFN-gamma results in resistance of uveal melanoma cells to granule-mediated lysis by cytotoxic lymphocytes.
|
Academic Article
|
A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells.
|
Academic Article
|
Detection of human perforin by ELISpot and ELISA: ex vivo identification of virus-specific cells.
|
Academic Article
|
Human and mouse granzyme A induce a proinflammatory cytokine response.
|
Academic Article
|
The effect of beta-endorphin on natural cytotoxicity and antibody dependent cellular cytotoxicity.
|
Academic Article
|
Natural cytotoxicity in systemic lupus erythematosus: mechanisms of suppression by inhibitory serum factors.
|
Academic Article
|
Deficient interleukin-2-activated killer cell cytotoxicity in patients with systemic lupus erythematosus.
|
Academic Article
|
Human perforin permeabilizing activity, but not binding to lipid membranes, is affected by pH.
|
Academic Article
|
Enrichment of natural killer cells by negative selection: comparison to Percoll gradient separation method.
|
Academic Article
|
Abnormal interferon modulation of natural cytotoxicity in systemic lupus erythematosus. Relation to suppressive serum factors.
|
Academic Article
|
Telltale mouth flora: a clue to the diagnosis of factitious recurrent thigh abscesses.
|
Academic Article
|
Antiphospholipid antibodies associated with retinal vascular disease.
|
Academic Article
|
Enhancement of natural cytotoxicity by beta-endorphin.
|
Academic Article
|
Characterization of E-rosette-positive Fc-receptor-bearing cells by flow cytometry.
|
Academic Article
|
Perforin rapidly induces plasma membrane phospholipid flip-flop.
|
Academic Article
|
Separation of natural and antibody-dependent cytotoxicity by differential reactivity of human mononuclear cell Fc receptors with IgG.
|
Academic Article
|
T gamma subset specificity of lymphocyte reactive factors in juvenile rheumatoid arthritis and systemic lupus erythematosus sera.
|
Academic Article
|
Serine and cysteine proteases are translocated to similar extents upon formation of covalent complexes with serpins. Fluorescence perturbation and fluorescence resonance energy transfer mapping of the protease binding site in CrmA complexes with granzyme B and caspase-1.
|
Academic Article
|
A case of Guillain-Barré syndrome with immunologic abnormalities.
|
Academic Article
|
Lymphocytotoxic antibodies in Guillain-Barré syndrome.
|
Academic Article
|
Flow cytometry and cytoadherence studies of sera from children with juvenile rheumatoid arthritis and normal controls.
|
Academic Article
|
Human granzyme B is essential for DNA fragmentation of susceptible target cells.
|
Academic Article
|
The biology of cytotoxic cell granule exocytosis pathway: granzymes have evolved to induce cell death and inflammation.
|
Academic Article
|
Granzyme B-induced and caspase 3-dependent cleavage of gelsolin by mouse cytotoxic T cells modifies cytoskeleton dynamics.
|
Academic Article
|
Phytohemagglutinin induced proliferation by aged lymphocytes: reduced expression of high affinity interleukin-2 receptors and interleukin-2 secretion.
|
Academic Article
|
Extracellular activities of human granzyme A. Monocyte activation by granzyme A versus alpha-thrombin.
|
Academic Article
|
Granule-mediated killing: pathways for granzyme B-initiated apoptosis.
|
Academic Article
|
Apoptosis induced by granzyme B-glycosaminoglycan complexes: implications for granule-mediated apoptosis in vivo.
|
Academic Article
|
Human granzyme B mediates cartilage proteoglycan degradation and is expressed at the invasive front of the synovium in rheumatoid arthritis.
|
Academic Article
|
Hepatic natural killer cells exclusively kill splenic/blood natural killer-resistant tumor cells by the perforin/granzyme pathway.
|
Academic Article
|
Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism.
|
Academic Article
|
Right place, right time.
|
Academic Article
|
Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events.
|
Academic Article
|
Mcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cells.
|
Academic Article
|
Deregulation of mitochondrial membrane potential by mitochondrial insertion of granzyme B and direct Hax-1 cleavage.
|
Academic Article
|
Human perforin employs different avenues to damage membranes.
|
Academic Article
|
D-penicillamine-induced myasthenia gravis in rheumatoid arthritis.
|
Academic Article
|
Induction of lymphokine activated killer cells in serum-free medium.
|
Academic Article
|
Glomerulosclerosis in the sudden infant death syndrome.
|
Academic Article
|
Effects of MACPF/CDC proteins on lipid membranes.
|
Academic Article
|
Granzyme A produced by ?(9)d(2) T cells induces human macrophages to inhibit growth of an intracellular pathogen.
|
Academic Article
|
Elucidating sources and roles of granzymes A and B during bacterial infection and sepsis.
|
Academic Article
|
Membrane pore formation at protein-lipid interfaces.
|
Academic Article
|
Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes.
|
Academic Article
|
Can foot orthoses prevent hallux valgus deformity in rheumatoid arthritis? A randomized clinical trial.
|
Academic Article
|
Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion.
|
Academic Article
|
Granzymes A and K differentially potentiate LPS-induced cytokine response.
|
Academic Article
|
Granzyme A Contributes to Inflammatory Arthritis in Mice Through Stimulation of Osteoclastogenesis.
|
Academic Article
|
Pit cells exclusively kill P815 tumor cells by the perforin/granzyme pathway.
|
Concept
|
Bcl-2-Like Protein 11
|
Concept
|
Caspase Inhibitors
|
Concept
|
Myeloid Cell Leukemia Sequence 1 Protein
|